Theory and Evidence for Platelet Therapy of the Aging Face

Platelet preparations are autologous blood concentrates with supraphysiologic concentrations of platelets with or without leukocytes used in various clinical applications including regenerative medicine, wound healing, and facial rejuvenation. Their use harnesses the important role of platelets and their secretory products in immunoregulation, wound healing, angiogenesis, and tissue remodeling. The use of platelet preparations has been long documented in orthopaedic surgery, maxillofacial surgery, and other fields, but over the years research has increased in their application to facial plastic surgical techniques. Here we review the various formulations of platelet rich concentrates, their applications to facial skin rejuvenation, wound healing, scar reduction, and tissue fill as documented in the literature since 2018.

Contemporary model of dealing with scars in cosmetology and aesthetic medicine

Scars on the body can affect both the aesthetic and health aspects. They are formed during the healing of wounds, and the place where the defect is formed is replaced by fibrous connective tissue. Due to the structure, scars can be divided into: atrophic, linear, hypertrophic and keloid. The aim of the study was to present various types of scars and the possibilities of therapy in modern cosmetology and aesthetic medicine. The methods of scar reduction depend on the morphology of the lesions and may be pharmacological, mechanical or chemical. Despite the many possibilities offered by the aesthetic market, complete removal of the scar is often impossible, however, the use of combined therapies may lead to its significant reduction, flattening or discoloration. Scar reduction not only improves the external appearance, but also helps to regain psychological comfort of people as well as increase self-confidence.