mass enhancement
Recently Published Documents


TOTAL DOCUMENTS

250
(FIVE YEARS 42)

H-INDEX

32
(FIVE YEARS 3)

Author(s):  
Almila Coskun Bilge ◽  
Pinar Ilhan Demir ◽  
Hale Aydin ◽  
Isil Esen Bostanci

Objective: Our single-centre retrospective study aimed to evaluate the relationship between magnetic resonance (MR)-directed ultrasound (MDUS) detectability and magnetic resonance imaging (MRI) findings of non-mass enhancement (NME) lesions, regarding the morphologic and enhancement features, the distance from the skin and nipple, and the presence of concomitant landmarks. Methods: A total of 350 MRI-detected NME lesions that were determined between January 2015 and May 2019 and subsequently underwent MDUS were analyzed. The MRI findings, biopsy results, and follow-up outcomes of lesions were recorded. The correlation between the MRI findings of the lesions and MDUS detectability was analyzed. Results: One hundred fourteen (32.6%) of the 350 lesions had a counterpart in the MDUS. Respectively, 66 (37.9%), 38 (43.2%) and 59 (38.3%) of the lesions detected in MDUS were larger than 20 mm in size, with a distance of less than 20 mm to the nipple and 15 mm to the skin. The lesion size and lesion distance to the nipple and skin were significantly associated with a US correlate (p < 0.05). The MDUS detection rate was significantly higher in NME lesions with MR findings including diffuse distribution (p < 0.001), clustered-ring enhancement pattern (p < 0.001), washout kinetic curve (p = 0.006), and MR-BIRADS category 5 (p < 0.001). Multivariate logistic regression showed that only the clustered-ring enhancement pattern was significantly associated with an MDUS correlation (p < 0.001). Conclusion: Statistically significant correlations were found between the size, distance to the nipple and skin, distribution pattern, enhancement pattern and kinetic curve of the NME lesions on MRI and ultrasound detectability. Advances in knowledge: We found that clustered-ring enhancement patterns were significantly more frequent in MR-directed US detectable lesions.


2021 ◽  
Vol 104 (14) ◽  
Author(s):  
Matthew R. Carbone ◽  
Andrew J. Millis ◽  
David R. Reichman ◽  
John Sous

Author(s):  
Ola Magdy Mohamed Shetat ◽  
Amr Farouk Ibrahim Moustafa ◽  
Sara Zaitoon ◽  
Mohamed Ibrahim Ibrahim Fahim ◽  
Ghada Mohamed ◽  
...  

Abstract Background Breast microcalcifications are one of the most difficult mammographic findings to assess. The purpose of this study is to assess the ability of contrast-enhanced spectral mammography in the assessment of suspicious microcalcification and in predicting the grade of DCIS. Methods Three hundred and forty cases with suspicious microcalcification were reviewed in this study. We excluded 160 cases associated with masses. We enrolled 180 cases for analysis of suspicious microcalcification on mammograms with no underlying masses. We reviewed the microcalcification for their morphology, distribution, and associated pathological enhancement according to BI-RADS lexicon with pathology results reviewed and classified into benign and malignant which subdivided into low, intermediate, or high-grade DCIS or invasive carcinoma. Results Three hundred and forty cases with suspicious microcalcification were reviewed in this study. We excluded 160 cases associated with masses. Forty-five of 180 cases were benign, and 135/180 cases were malignant. Twenty-five of 135 cases were diagnosed as invasive breast carcinomas while 110/135 were ductal carcinoma in situ. From the latter, 110 patients with DCIS, 22/110 cases were low grade, 11/110 cases were intermediate grade, and 77/110 cases were high grade (44 with micro-invasion). A total of 25 invasive carcinomas showed pathological non-mass enhancement, 76/77 cases of high-grade DCIS, and 6/11 cases of intermediate-grade DCIS. No abnormal enhancement appeared with benign entities, low-grade DCIS, and 5/11 cases of intermediate DCIS. The diagnostic performance of CESM in anticipation of high grade in DCIS patients was sensitivity of 98%, specificity of 81.8%, and accuracy of 93.1%. CESM sensitivity, specificity, and accuracy in prediction of invasiveness or high-grade DCIS were 98.5%, 81.8%, and 87.5%, respectively. Conclusion CESM can provide a fundamental contribution in the evaluation of suspicious microcalcification as high-grade DCIS or invasive component can present by non-mass enhancement, but enhancement paucity is favorable to diagnose benign lesion or non-invasive/low-grade DCIS.


2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Oliver J. Clark ◽  
Friedrich Freyse ◽  
Irene Aguilera ◽  
Alexander S. Frolov ◽  
Andrey M. Ionov ◽  
...  

AbstractTopological phases of matter offer exciting possibilities to realize lossless charge and spin information transport on ultrafast time scales. However, this requires detailed knowledge of their nonequilibrium properties. Here, we employ time-, spin- and angle-resolved photoemission to investigate the ultrafast response of the Sb(111) spin-polarized surface state to femtosecond-laser excitation. The surface state exhibits a giant mass enhancement which is observed as a kink structure in its energy-momentum dispersion above the Fermi level. The kink structure, originating from the direct coupling of the surface state to the bulk continuum, is characterized by an abrupt change in the group velocity by ~70%, in agreement with our GW-based band structure calculations. Our observation of this connectivity in the transiently occupied band structure enables the unambiguous experimental verification of the topological nature of the surface state. The influence of bulk-surface coupling is further confirmed by our measurements of the electron dynamics, which show that bulk and surface states behave as a single thermalizing electronic population with distinct contributions from low-k electron-electron and high-k electron-phonon scatterings. These findings are important for future applications of topological semimetals and their excitations in ultrafast spintronics.


2021 ◽  
pp. 028418512110307
Author(s):  
Yunju Kim ◽  
Hae Kyoung Jung ◽  
Ah Young Park ◽  
Kyung Hee Ko ◽  
Hyunkyung Jang

Background Successful surgical treatment for localized breast cancer can depend on accurate diagnosis for accompanying non-mass enhancement (NME) on preoperative breast magnetic resonance imaging (MRI). Purpose To evaluate the diagnostic value of mammography for accompanying NME adjacent to index cancer on preoperative breast MRI Material and Methods Among 569 consecutive patients who underwent preoperative breast MRI from January 2016 to August 2018 for ultrasound-guided biopsy-proven breast cancer, 471 patients who underwent initial mammography and subsequent surgery were finally included. Two radiologists retrospectively reviewed preoperative MRI findings of the 471 patients and detected accompanying NME adjacent to index cancer. MRI, mammography, and histopathology findings of the accompanying NME were evaluated using Pearson’s chi-square test, Mann–Whitney U test, and logistic regression analysis. The area under the receiver operating characteristic curve (AUC) of MRI and combined MRI and mammography was calculated in differentiating benign from malignant accompanying NME. The reference standard was surgical pathologic findings. Results MRI revealed 93 accompanying NME lesions in 92 (19.5%) of the 471 patients, showing 55 (59.1%) malignant and 38 (40.9%) benign lesions. On multivariate analysis, malignant NME lesions were more associated with mammography-positive findings ( P = 0.000), clumped or clustered ring internal enhancement ( P = 0.015), and extensive intraductal component presence of index tumor ( P = 0.007) compared with benign lesions. The AUC increased after correlation with mammography showing 0.649 (95% confidence interval [CI] 0.533–0.765) for MRI and 0.833 (95% CI 0.747–0.919) for combined MRI and mammography. Conclusion Mammography is valuable in predicting malignancy for accompanying NME on preoperative breast MRI.


Author(s):  
U. Nazir ◽  
Nidal H. Abu-Hamdeh ◽  
M. Nawaz ◽  
Sayer Obaid Alharbi ◽  
Waqar Khan

2021 ◽  
Vol 3 (2) ◽  
pp. 77-87
Author(s):  
Wolfgang Buchberger ◽  
Willi Oberaigner ◽  
Christian Kremser ◽  
Kurt Gautsch ◽  
Uwe Siebert

Objectives: The purpose of this study was to assess the accuracy of contrast-enhanced magnetic resonance imaging and diffusion-weighted imaging in distinguishing benign from malignant non-mass-like breast lesions. Methods: 103 lesions showing non-mass-like enhancement in 100 consecutive patients were analyzed. Distribution, internal enhancement patterns, and contrast kinetic curve patterns were classified according to the BI-RADS lexicon. Apparent diffusion coefficient (ADC) values were obtained from manually placed regions of interest (ROIs) on diffusion-weighted images. The optimal ADC value threshold for the distinction between benign and malignant lesions was determined by ROC analysis. Univariate and multivariate analyses were performed to identify independent predictors of malignancy, and the probability of malignancy was calculated for various combinations of findings. Histological diagnosis obtained by means of core needle biopsy was used as gold standard. Results: According to the univariate and multivariate analysis, odds ratios for malignancy were significantly elevated for clumped or clustered ring internal enhancement and low ADC values (p < 0.001), whereas distribution patterns and contrast kinetic patterns were not significantly correlated with benignity or malignancy. In non-mass lesions with homogeneous or heterogeneous internal enhancement and ADC values greater than 1.26×10-3mm2/s, no malignancy was detected, while all other combinations of findings had a probability of malignancy ranging from 22.2 to 76.6%. Conclusions: A combination of BI-RADS descriptors of internal enhancement and ADC values is useful for the differential diagnosis of lesions showing non-mass enhancement. Lesions with homogeneous or heterogeneous enhancement and high ADC can be followed up, while all other lesions should be biopsied. Doi: 10.28991/SciMedJ-2021-0302-1 Full Text: PDF


2021 ◽  
Vol 103 (16) ◽  
Author(s):  
Zhi Wang ◽  
Oleksandr I. Malyi ◽  
Xingang Zhao ◽  
Alex Zunger

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
D. Valentinis ◽  
J. Zaanen ◽  
D. van der Marel

AbstractA highlight of Fermi-liquid phenomenology, as explored in neutral $$^3$$ 3 He, is the observation that in the collisionless regime shear stress propagates as if one is dealing with the transverse phonon of a solid. The existence of this “transverse zero sound” requires that the quasiparticle mass enhancement exceeds a critical value. Could such a propagating shear stress also exist in strongly correlated electron systems? Despite some noticeable differences with the neutral case in the Galilean continuum, we arrive at the verdict that transverse zero sound should be generic for mass enhancement higher than 3. We present an experimental setup that should be exquisitely sensitive in this regard: the transmission of terahertz radiation through a thin slab of heavy-fermion material will be strongly enhanced at low temperature and accompanied by giant oscillations, which reflect the interference between light itself and the “material photon” being the actual manifestation of transverse zero sound in the charged Fermi liquid.


Sign in / Sign up

Export Citation Format

Share Document