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Author(s):  
Pankaj D. Rathod ◽  
Rashmi T. Kamdar ◽  
Het J. Shah

The new progressions in the Internet of Things (IoT) and Artificial Intelligence (AI) changed the traditional medical care framework into intelligent medical care. By consolidating key innovations, for example, IoT and AI, clinical benefits can be improved. The intermingling of IoT and AI offers various freedoms in the medical care area. the current survey article presents AI and IoT innovations in various fields. Like AI and IoT are utilized to recognize infections at introductory stages, keepa record of the relative activity of exercises, is extremely useful at the hours of crisis, deals with physical just as psychological wellness. It will likewise save a ton of cost and will be utilized for enormous scope.


2021 ◽  
Author(s):  
◽  
Zara Fong

<p>Birth, growth, death and decay constitute an inherent cycle in nature that maintains balance and enables ecosystems to adapt to external changes. Although death and decay are essential for birth and growth of the following generations, these disappearing stages are often ignored and unappreciated in manmade cultures and practices. Especially in design, in the era of mass production, the pursuit of quantity and uniformity inevitably link to many environmental issues. As a desperate response, bio-based materials have recently gained attention as alternatives to fossil-derived materials or new resources for industry, and rapid advancement of additive manufacturing (AM) has revolutionised conventional methods of manufacturing, enabling low volume, quality-focused production. This research discusses the pioneering incorporation of the stages of death and decay into design practices, exploiting a novel opportunity provided by the two key innovations, AM technologies and bio-based materials. A series of digital plants which employ and undergo the two degenerative stages are designed and produced using digital and scientific processes, and their transformative degradation induced by environmental stimuli, including humidity and UV, is demonstrated. The programmed visual and physical deformations suggest that a purposeful and systematic introduction of the two stages to the current design and manufacturing practices could offer a more sustainable and responsible approach to creation and production. They also exhibit new possibilities for digital processes, including parametric modelling and 3D-printing, through an integrative combination with bio-based materials.</p>


2021 ◽  
Author(s):  
◽  
Zara Fong

<p>Birth, growth, death and decay constitute an inherent cycle in nature that maintains balance and enables ecosystems to adapt to external changes. Although death and decay are essential for birth and growth of the following generations, these disappearing stages are often ignored and unappreciated in manmade cultures and practices. Especially in design, in the era of mass production, the pursuit of quantity and uniformity inevitably link to many environmental issues. As a desperate response, bio-based materials have recently gained attention as alternatives to fossil-derived materials or new resources for industry, and rapid advancement of additive manufacturing (AM) has revolutionised conventional methods of manufacturing, enabling low volume, quality-focused production. This research discusses the pioneering incorporation of the stages of death and decay into design practices, exploiting a novel opportunity provided by the two key innovations, AM technologies and bio-based materials. A series of digital plants which employ and undergo the two degenerative stages are designed and produced using digital and scientific processes, and their transformative degradation induced by environmental stimuli, including humidity and UV, is demonstrated. The programmed visual and physical deformations suggest that a purposeful and systematic introduction of the two stages to the current design and manufacturing practices could offer a more sustainable and responsible approach to creation and production. They also exhibit new possibilities for digital processes, including parametric modelling and 3D-printing, through an integrative combination with bio-based materials.</p>


2021 ◽  
Author(s):  
Jason Lenihan ◽  
Matthew Mailloux ◽  
Aaron Beeler

We report the development of a multigram scale total synthesis of heterodimeric β-truxinic imides piperarborenines C-E using a catechol-mediated diastereoselective intramolecular [2+2] photocycloaddition. Key innovations lie in the use of (1) catechol as a highly selective auxiliary for the robust and scalable synthesis of homo- and heterodimeric β-truxinates, (2) UV LEDs for direct excitation in the [2+2] cycloaddition step, and (3) a bis pentafluorophenyl ester and LDA for the challenging installation of the syn dihydropyridinone imides. This approach is exceptionally scalable – requiring minimal chromatography, no photocatalysts, and no cryogenic conditions - and will enable thorough evaluation of the biological properties and anticancer profiles of piperaborenines C-E and derivatives thereof.


2021 ◽  
Vol 5 (OOPSLA) ◽  
pp. 1-30
Author(s):  
Ziqiao Zhou ◽  
Michael K. Reiter

Noninterference measurement quantifies the secret information that might leak to an adversary from what the adversary can observe and influence about the computation. Static and high-fidelity noninterference measurement has been difficult to scale to complex computations, however. This paper scales a recent framework for noninterference measurement to the open-source RISC-V BOOM core as specified in Verilog, through three key innovations: logically characterizing the core’s execution incrementally, applying specific optimizations between each cycle; permitting information to be declassified, to focus leakage measurement to only secret information that cannot be inferred from the declassified information; and interpreting leakage measurements for the analyst in terms of simple rules that characterize when leakage occurs. Case studies on cache-based side channels generally, and on specific instances including Spectre attacks, show that the resulting toolchain, called DINoMe, effectively scales to this modern processor design.


2021 ◽  
Vol 7 (2) ◽  
pp. 711-712
Author(s):  
Niels Grabow ◽  
Volkmar Senz ◽  
Klaus-Peter Schmitz

Abstract The coordinated research project “RESPONSE - Partnership for Innovation in Implant Technology”, which is one of ten BMBF-funded research consortia within the program “Twenty20 - Partnership for Innovation”, is active in the field of medical device innovation. The consortium is currently in the process of unfolding its transfer phase. This involves a portfolio of key innovations for novel medical devices, technologies and processes. Also, RESPONSE is aiming at participative technology development, integrating perspectives of patients, developers, as well as systems and innovation researchers. Particular challenges are arising from the current re-prioritization and re-scheduling of project roadmaps in order to manage and alleviate the effects of the corona crisis.


2021 ◽  
Author(s):  
Gajaba Ellepola ◽  
Marcio R. Pie ◽  
Rohan Pethiyagoda ◽  
James Hanken ◽  
Madhava Meegaskumbura

Although large diversifications of species occur unevenly across space and evolutionary lineages, the relative importance of their driving mechanisms, such as climate, ecological opportunity and key innovations, remains poorly understood. Here, we explore the remarkable diversification of rhacophorid frogs, which represent six percent of global amphibian diversity, utilize four distinct reproductive modes, and span a climatically variable area across mainland Asia, associated continental islands, and Africa. Using a complete species-level phylogeny, we find near-constant diversification rates but a highly uneven distribution of species richness. Montane regions on islands and some mainland regions have higher phylogenetic diversity and unique assemblages of taxa; we identify these as cool-wet refugia. Starting from a centre of origin, rhacophorids reached these distant refugia by adapting to new climatic conditions (niche evolution-dominant), especially following the origin of key innovations such as terrestrial reproduction (in the Late Eocene) or by dispersal during periods of favourable climate (niche conservatism-dominant).


Pharmacy ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 156
Author(s):  
Daniel Malone ◽  
Kirsten Galbraith ◽  
Paul J. White ◽  
Betty Exintaris ◽  
Joseph A. Nicolazzo ◽  
...  

Whilst curriculum revision is commonplace, whole degree transformation is less so. In this paper we discuss the rationale, design and implementation of a unique pharmacy program by a research-intensive faculty. The new Monash pharmacy curriculum, which had its first intake in 2017, was built using a range of key innovations that aimed to produce graduates that demonstrate key conceptual understanding and all the skills required to deliver world-best patient outcomes. The key elements of the re-design are outlined and include the process and principles developed, as well as key features such as a student-centred individualised program of development arranged around specific, authentic tasks for each skill and earlier enhanced experiential placements where students become proficient in entrustable professional activities. It is hoped the dissemination of this process, as well as the lessons learnt in the process, will be useful to others looking to transform a health curriculum.


2021 ◽  
pp. 267-286
Author(s):  
Sacha Golob

The Phenomenological tradition is defined by its attempt to rethink the self and self-awareness. This chapter provides an overview of some of the fundamental developments within that tradition running from Husserl, Heidegger, Sartre and Merleau-Ponty to later writers such as Henry. I begin by sketching the key features: its relationship to naturalistic and transcendental approaches, the centrality of the first person perspective, and the hierarchical model which is central to Phenomenology’s vision of experience. I next introduce the specifics of Phenomenology’s picture of self-awareness, positioning it between the spectatorial model found in Brentano and a Kantian intellectualism. I then turn to some key innovations: Sartre’s notion of non-positional self-consciousness, Heidegger on the links between the self and the social, and finally Merleau-Ponty’s conception of embodiment.


2021 ◽  
Vol 18 (1) ◽  
pp. 223-242
Author(s):  
NM PISA ◽  

Given the overtime decline in rail freight volumes in emerging economies, this review explores key measurable innovations, in rail freight transportation that have improved rail logistics efficiency in developed countries. A systematic approach was used in this review to select and extract data from published journal articles. Journal articles included were only those that showed and reported impact of key innovations on various rail freight efficiency outcomes. There are 4 (four) innovation clusters namely; i.) investment; ii.) operational management; iii.) policy and or regulatory framework; and iv.) technology and automation. These clusters were reported to have a positive impact on rail freight efficiency measures including transport costs, routing, rolling stock rotation and real-time dispatching, customer satisfaction, rail freight infrastructure and improved railway safety. This article highlights that opportunities exist to implement various innovations in emerging countries. However, the success of these innovations, in improving rail freight efficiency, is dependent on context and evidence-driven assessments of the challenges related to rail freight operational efficiency in the different emerging economies. Additionally, governmental commitment to implementation of sound policies and strong collaboration with various stakeholders, including the private sector, is required to successfully implement innovations and improve rail freight efficiency.


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