Hospitalization Expenses and Influencing Factors for Inpatients with Ischemic Heart Disease in Iran: A Retrospective Study

Background: Ischemic heart disease (IHD) is the leading cause of death and disability worldwide and in Iran, which imposes a heavy financial burden both on patient’s family and society. Objectives: This study aimed to analyze the direct medical costs of inpatients with IHD and its influencing factors in Iran in 2020. Methods: The sample of this cross-sectional study included 41,357 patients with IHD selected from the hospital information system (HIS) of the Iran Health Insurance Organization from August 23, 2019, to June 20, 2020. The study used the claims data of these patients, which included their demographics, length of stay (LOS), intensive care unit (ICU) admission, hospital accreditation grade, hospital ownership type, and patient discharge status. The multiple linear regression model was employed to evaluate the relationship between hospitalization costs and the associated factors. All statistical tests were conducted at the significance level of P < 0.05 using the R 3.6.3 software. Results: The mean age of patients was 63.95 ± 12.63 years old, and most of them were male (54.4%). The mean hospitalization cost per patient and per day was 586.42 ± 472.51 USD and 103.64 ± 100.29 USD, respectively. Moreover, the mean LOS was 4.92 days. Drugs and consumable medical supplies, as well as nursing and hoteling services, had the highest shares of hospitalization costs (29.54% and 29.4%, respectively). The hospitalization costs of patients with IHD were higher among men (β = 1.24), age 61 - 70 years (β = 1.38), LOS ≥ 5 (β = 2.92), ICU admission (β = 1.62), Iranian health fund (β = 1.21), and private hospitals (β = 1.91). Top-grade and first-grade hospitals had higher costs compared to grade 2 (β = 0.67), grade 3 (β = 0.35), and grade 4 (β = 0.72) hospitals. Deceased patients had also higher costs than patients with complete recovery (β = 0.63), relative recovery (β = 0.59), follow-up (β = 0.51), transfer to other medical centers (β = 0.44), and discharge against medical advice (DAMA) (β = 0.62). Conclusions: According to the results, shortening the LOS and controlling the high costs of drugs and consumable medical supplies are among the main strategies to reduce high hospitalization costs.

Hepatitis B Virus Infection in Vaccinated Children and Adolescents with HBsAg-positive Parents: Is Routine Vaccination Sufficient?

Background: Hepatitis B virus (HBV) is a severe public health problem in Iran. This study was conducted to investigate the intrafamilial transmission of HBV in vaccinated children whose one or both parents were positive for hepatitis B surface antigen (HBsAg). Methods: In a study with retrospective cohort design, 110 exposed cases with HBsAg-positive parent(s) were compared with 110 unexposed controls of the same sex and age groups. The participants were directly asked about demographic characteristics, medical history, and vaccinations. Blood samples were collected and analyzed for HBV infection markers using the ELIZA method. Results: Overall, 1.8% HBsAg (P = 0.15) and 13.6% hepatitis B core antibody (HBcAb) (P < 0.0001) positivity rates were detected in the exposed group. The hepatitis B surface antibody titer (HBsAb) showed that 34.5% of cases and 56.3% of controls had HBsAb levels > 10 IU/L. There was a significant difference in the protective HBsAb level between the two groups (P < 0.0001). There were significant associations between HBsAb level and gender in the exposed group and decreased HBsAb levels and age. Conclusions: The high rate of positive HBcAb and HBsAg and decreasing HBsAb levels with age in this study indicate that routine childhood vaccination programs are inadequate in preventing HBV transmission and vaccine routes changing or further booster vaccination is essential. Effective case finding in vaccinated children with HBsAg-positive parents, intradermal vaccination, and hepatitis B immunoglobulin in newborns with HBsAg-positive fathers are suggested.

Relationship Between Pharmaceutical Knowledge and Probability of Medication Errors Among Nurses: A Cross-sectional Study in the Northwest of Iran in 2020

Background: Patient safety is a major concern for health care professionals. Medication errors have been considered a major indicator of health care quality. The lack of pharmacological knowledge is a cause of medication error among nurses. Objectives: The purpose of this study was to investigate the relationship between pharmacological knowledge and the probability of medical errors in nurses working in Urmia hospitals in 2020. Methods: This cross-sectional study included 490 nurses randomly selected from among those working in hospitals of Urmia in 2020. The data collection tool was a multiple-choice questionnaire about knowledge and pharmacological skills consisting of 3 sections: demographic information, nurses’ drug knowledge, and the confidence level of response in nurses. To analyze questions and hypotheses via SPSS version 21, the t-test and analysis of variance (ANOVA) were employed. Results: The highest pharmaceutical knowledge scores of nurses were related to methods of administration (2.9 ± 1.01 [72.56%]), and the lowest score was related to drug management (1.05 ± 0.63 [52.84%]). The mean of error probability was very low in 28.81% of nurses, low in 37.66%, high in 11.34%, and very high in 22.85%. Pharmaceutical knowledge had a significant relationship with gender, wards, type of hospital, and number of children (P < 0.05 for all). Conclusions: Since the nurses’ level of pharmaceutical knowledge has an important role in the correct prescription of medicine, we suggest that nurse managers and educational supervisors in the field of nursing use in-service training programs and prepare training booklets and posters to promote nurses’ pharmaceutical knowledge in this field.

Utilization of Preventive Care Services at a University Hospital in Saudi Arabia

Background: Chronic diseases have significant impacts on health systems worldwide and are a leading cause of death. Early diagnosis and treatment of chronic diseases are the best ways to reduce mortality and morbidity. Objectives: The aim of this study was to evaluate public access to preventive services for chronic diseases in Jeddah, Saudi Arabia. Methods: A survey of university hospital visitors was conducted in 2019. Participants were randomly selected and asked to fill a 16-question survey, including demographics, health care utilization, and type of preventive services. The chi-square test (SPSS) was used to identify any significant association between age and gender using the variable of preventive screening or counseling. Results: The majority of individuals who completed the survey (250 participants) were young, married, and male bachelor’s degree holders. About 71% of the participants received counseling services for either smoking, physical activity, weight, diet, or sleeping. More than half (58%) had undergone screening services, including breast cancer, colon cancer, diabetes, hypertension, or weight management. Chi-square analysis showed that females had a significant (P < 0.01) positive statistical relationship with the utilization of diabetes and breast cancer screening services, while males were more associated (P < 0.01) with smoking and weight-related counseling than females. Conclusions: The study demonstrated an insufficient use of preventive services and that sociodemographic differences (such as age and gender) could influence the utilization of various preventive services. Females were significantly positively associated with breast cancer and diabetes-related preventive services as these diseases are highly prevalent among females. Public education and awareness campaigns are needed to broadcast the importance of preventive services and promote better understanding and management of chronic diseases.

Potential Risk Factors for Length of Hospitalization in COVID-19 Patients: A Cross-sectional Study

Background: Identifying the potential risk factors of the length of stay in hospital (LOSH) in COVID-19 patients could help the health system meet future demand for hospital beds. Objectives: This study aimed to determine the factors affecting the length of stay in hospital in COVID-19 patients in Hamadan, the west of Iran. Methods: This cross-sectional study recruited 512 hospitalized COVID-19 patients in Hamadan city. Demographic, clinical, and medical laboratory characteristics of the patients and their survival status were assessed by a checklist. Univariate and multiple negative binomial regressions were used by Stata 12. Results: The median hospitalization length for COVID-19 patients was five days (range: 0 to 47). In the discharged patients, the adjusted incidence rate ratios (95% CI) of LOSH for females, rural residents, patients with a history of diabetes and cardiovascular disease, SPO2 less than 88%, prothrombin time higher than 13 s, platelet count lower than 130 × 1000 µL, blood sugar higher than 105 mg/dL, and intensive care unit experience were 1.16 (1.03, 1.44), 1.22 (1.03, 1.44), 1.43 (1.07, 1.92), 1.41 (1.23, 1.61), 0.82 (0.71, 0.93), 1.32 (1.11, 1.56), 1.18 (1.03, 1.36), and 1.85 (1.59, 2.17) compared to their references, respectively. Conclusions: Our study added new insight into LOSH determining factors that could be used for future planning in combating the need for hospital beds. The present study revealed that some demographic, social, and clinical variables could increase the IRR of a more extended hospital stay.

The Effect of Health Promotion Educational Interventions on Self-Care Behaviors of Nutrition and Physical Activity Among Universities Staff in Southeastern Iran

Background: A workplace has an important role in staff health. Besides, it is a suitable place for performing interventions to reduce the risk of suffering from health problems associated with physical inactivity and overweight, and to reduce risks of cardiovascular and non-communicable diseases. Objectives: This study aims to investigate the effects of health promotion educational interventions on self-care behaviors of nutrition and physical activity among the selected university staff in Zahedan during the COVID-19 pandemic. Methods: The present quasi-experimental research was conducted in 2020-2021 in Zahedan, southeastern Iran. The control and intervention groups included a random selectionof 110 and 144 non-academic staff members of Zahedan University of Medical Sciences (ZAUMS) as well as Sistan and Baluchestan University (SBU), respectively. At the beginning of the COVID-19 pandemic, an online researcher-made questionnaire (Porsline, https://survey.porsline.ir) (CVR: 92%; CVI: 90%; reliability: 85%) was uploaded, which had been already approved. Besides, educational booklets were provided to the intervention group via WhatsApp and Soroush messengers, through which the participants were allowed to ask their questions after every session. One month after the intervention, the online questionnaires were re-uploaded on Porsline and recompleted by the participants. The results were analyzed using SPSS V21.0. Results: The results indicated that the self-care behaviors of nutrition and physical activity increased significantly in terms of awareness, attitude, and performance among the intervention group participants after conducting the educational intervention (P-value < 0.05). Accordingly, the educational intervention resulted in an increase in the level of awareness, attitude, and performance of nutrition and physical activity among the university staff of the intervention group. Besides, the performance of physical activity was significantly affected not only by the intervention (P < 0.001) but also by work experience (P < 0.001). In addition, nutrition behavior was significantly better in female staff than male staff (P = 0.048), but there was no significant correlation between gender and the intervention (P = 0.266). Conclusions: The educational program executed in the present study was shown to be effective in promoting self-care behaviors of nutrition and physical activity among the university staff. Thus, health programmers and policymakers can have a significant role in promoting staff health by executing interventional educational programs. Accordingly, the efficiency of the whole system will improve by adopting these strategies and programs.

Construction and Validation of Social Citizenship Index

Background: Social citizenship means creating a situation in which everyone can develop their full potential. Objectives: This study aimed to determine the social citizenship index with its various dimensions in selected countries. Methods: This study used a mixed-methods approach consisting of two phases. In the first phase, social citizenship items were extracted based on a systematic review of previous studies and interviews with experts using direct content analysis. In the second phase, the standardized index was assessed by performing the validity and reliability tests. To combine the dimensions, their values were standardized using the Z score. To analyze the data, factor analysis and normality tests were used. Results: The social citizenship index was categorized into four main dimensions, including health and education, livelihood, economic-political prosperity, and open society. In this study, 125 countries were categorized based on the Social Citizenship Index. The selected countries were classified into three categories based on the opinions of the research group and the cutting point of statistical quartiles: high (32 countries), medium (62 countries), and low (31 countries). Conclusions: It can be concluded that the social citizenship index with four main dimensions and 26 variables is a new tool that allows countries to be compared in the areas of providing welfare services to their citizens.

Determinants of Hypertension Self-management Behaviors: An Application of the Intervention Mapping Approach

Background: Hypertension is one of the key risk factors for several diseases. Objectives: The aim of this study was to determine the determinants of hypertension self-management behaviors (HSBs) based on intervention mapping approach. Methods: A cross-sectional study was conducted among 800 hypertensive patients in southwestern Iran in 2018. A structured questionnaire was applied for data collection. Data were analyzed using SPSS version 16. Results: The mean age of respondents was 58.25 years (SD: 12.10; age range: 30 - 74 years). The best predictors for HSBs were perceived barriers, outcome expectations, and self-efficacy. Conclusions: Our findings have implications for the evidence-based design of HSBs promotion interventions.

Knowledge and Practice of Pap Smear and Vaccination Regarding Human Papillomavirus Among Female Medical Students in Karachi, Pakistan

Background: Cervical cancer is the leading cause of women’s death in developing countries. The change in the epidemiological trends has been attributed to mass screening with the help of a Pap smear. Objectives: This study aimed to determine the knowledge level and practice regarding a Pap smear and human papillomavirus (HPV) vaccination among female medical students in Karachi, Pakistan. Methods: In this cross-sectional study, 147 participants were selected through multistage stratified random sampling. The knowledge level was categorized as adequate if the participants answered 60% of the items. Questionnaire validity was determined through Cronbach’s alpha value (α = 0.69). Binary logistic regression was applied to determine the factors associated with the knowledge level among the students. A confidence interval (CI) of 95% was considered with a margin of error of 5% and a P-value of 0.05 as statistically significant. Results: Most students (60.5%) had adequate knowledge regarding a Pap smear and HPV vaccination. Only 3.4% of the students underwent a Pap smear test. The most common factors contributing to the knowledge level were marriage (OR = 2.98; 95% CI: 1.23 - 11.09; P = 0.003), first academic year of students (OR = 10.78; 95% CI: 1.03 - 12.01; P = 0.046), family history of cancer (OR = 2.76; 95% CI: 1.34 - 7.90; P = 0.004), and family income less than < 100000 Pakistani Rupee (OR = 5.45; 95% CI: 2.09 - 9.06; P = 0.005). Conclusions: Being medical students studying in the first academic year, family history of cancer, and family income less than 100000 Pakistani Rupee had significant effect on knowledge gap about a Pap smear and HPV vaccination. There is a need for an increased level of knowledge in this regard by addressing the risk factors contributing to the knowledge level.

Psychometric Characteristics of a Questionnaire Measuring Hopefulness: An Exploratory and Confirmatory Factor Analysis Approach

Background: In the third millennium, which is called the information era, despite the technological growth and industrialization, lack of hopefulness is seen in the general population, especially among the youth. Therefore, hope is one of the critical issues that should be promoted among the youth. Objectives: This study was aimed at evaluating a hopefulness questionnaire among the youth. Methods: This cross-sectional study with an exploratory approach was carried out among the Iranian youth population in 2020. All students of Shahed University in Tehran (estimated as 5000 people) were considered the study population, 600 of whom were selected as the study sample by the simple random sampling method. For data collection, a researcher-made questionnaire was utilized. Data analysis was performed by SPSS v. 21 and LISREL v. 8.80. Alpha Cronbach coefficient was used to investigate the reliability of the questionnaire. Results: The results showed the adequate reliability of the hopefulness questionnaire. Also, the findings showed that three latent variables in the questionnaire had significantly larger values than the other factors. Therefore, with three latent factors, the hopefulness questionnaire was significantly saturated. Cronbach’s alpha coefficient for the 33 items of the questionnaire was 0.80. Conclusions: It was found that the questionnaire constructs are useful in predicting hopefulness intention. The scale consisted of three factors that did not completely replicate the factors found in previous studies. The use of this tool is recommended for all age groups.