Mathematical Model and Analysis of Corruption Dynamics with Optimal Control

In this study, a deterministic mathematical model that explains the transmission dynamics of corruption is proposed and analyzed by considering social influence on honest individuals. Positivity and boundedness of solution of the model are proved and basic reproduction number R 0 is computed using the next-generation matrix method. The analysis shows that corruption-free equilibrium is locally and globally asymptotically stable whenever R 0 < 1 . Also, the endemic equilibrium point is locally and globally asymptotically stable whenever R 0 > 1 . Then, the model was extended to optimal control, and some numerical simulations with and without optimal control are also performed to verify the theoretical analysis using MATLAB. Numerical simulation of optimal control model shows that the prevention and punishment strategy is the most effective strategy to reduce the dynamic transmission of corruption.

Numerical Solution of Three-Dimensional Transient Heat Conduction Equation in Cylindrical Coordinates

Heat equation is a partial differential equation used to describe the temperature distribution in a heat-conducting body. The implementation of a numerical solution method for heat equation can vary with the geometry of the body. In this study, a three-dimensional transient heat conduction equation was solved by approximating second-order spatial derivatives by five-point central differences in cylindrical coordinates. The stability condition of the numerical method was discussed. A MATLAB code was developed to implement the numerical method. An example was provided in order to demonstrate the method. The numerical solution by the method was in a good agreement with the exact solution for the example considered. The accuracy of the five-point central difference method was compared with that of the three-point central difference method in solving the heat equation in cylindrical coordinates. The solutions obtained by the numerical method in cylindrical coordinates were displayed in the Cartesian coordinate system graphically. The method requires relatively very small time steps for a given mesh spacing to avoid computational instability. The result of this study can provide insights to use appropriate coordinates and more accurate computational methods in solving physical problems described by partial differential equations.

Asumu Fractional Derivative Applied to Edge Detection on SARS-COV2 Images

Edge detection consists of a set of mathematical methods which identifies the points in a digital image where image brightness changes sharply. In the traditional edge detection methods such as the first-order derivative filters, it is easy to lose image information details and the second-order derivative filters are more sensitive to noise. To overcome these problems, the methods based on the fractional differential-order filters have been proposed in the literature. This paper presents the construction and implementation of the Prewitt fractional differential filter in the Asumu definition sense for SARS-COV2 image edge detection. The experiments show that these filters can avoid noise and detect rich edge details. The experimental comparison show that the proposed method outperforms some edge detection methods. In the next paper, we are planning to improve and combine the proposed filters with artificial intelligence algorithm in order to program a training system for SARS-COV2 image classification with the aim of having a supplemental medical diagnostic.

Applications of OHAM and MOHAM for Fractional Seventh-Order SKI Equations

In this article, a comparative study between optimal homotopy asymptotic method and multistage optimal homotopy asymptotic method is presented. These methods will be applied to obtain an approximate solution to the seventh-order Sawada-Kotera Ito equation. The results of optimal homotopy asymptotic method are compared with those of multistage optimal homotopy asymptotic method as well as with the exact solutions. The multistage optimal homotopy asymptotic method relies on optimal homotopy asymptotic method to obtain an analytic approximate solution. It actually applies optimal homotopy asymptotic method in each subinterval, and we show that it achieves better results than optimal homotopy asymptotic method over a large interval; this is one of the advantages of this method that can be used for long intervals and leads to more accurate results. As far as the authors are aware that multistage optimal homotopy asymptotic method has not been yet used to solve fractional partial differential equations of high order, we have shown that this method can be used to solve these problems. The convergence of the method is also addressed. The fractional derivatives are described in the Caputo sense.

Effects of Drugs Reabsorption Time Delays for a Pharmacokinetics Model in Humans

A three-compartmental delay model is formulated to describe the pharmacokinetics of drugs subjected to both intravenous and oral doses with reabsorptions by the central compartment. Model dynamics are analyzed rigorously, and two equilibrium points are obtained to be locally asymptotically stable under certain conditions. Time delays used as lags in reabsorption of drugs by central compartment from other two compartments caused rebounds or peaks and fluctuations in the time profiles for amounts of drug in all the compartments. Sensitivity analysis revealed that elimination rates decrease the amounts in all compartments. Furthermore, reabsorption rates cause superimposition at the initial phases of the drug amount profiles; subsequently, the quantities decrease in compartment one and increase in compartments two and three, respectively.

MHD Analysis of Couple Stress Hybrid Nanofluid Free Stream over a Spinning Darcy-Forchheimer Porous Disc under the Effect of Thermal Radiation

This article develops the semianalytical analysis of couple stress hybrid nanofluid free stream past a rotating disc by applying the magnetic flux effects and radiation of thermal energy. The analysis of such kind of mixed convective flow is most important due to numerous industrial applications such as electronic devices, atomic reactors, central solar energy equipment, and heat transferring devices. The impact of variable permeability is also considered in the study. The permeability of the disc obeys the Darcy-Forchheimer model. The hybrid nanofluid is composed of water, titanium dioxide, and aluminum oxide. The set of governing equations in the PDE form are transformed to couple ODEs by applying similarity transformations. The ODE set are solved by applying the technique of HAM. The graphs of impacts of numerous physical parameters over momentum, energy, and concentration profiles are drawn in computer-based application Mathematica 11.0.1. In the sundry physical parameters, the porosity parameter, Reynolds number, inertial parameter, Prandtl number, Schmidt number, couple stress, and quotient of rotational momentum to elongating rate are included. During the analysis, it is found that the momentum profile of the couple stress hybrid nanofluid enhances with local inertial parameter, couple stress parameter, porosity parameter, and Reynolds number but declines for the growth in Hartmann number. Heat transfer rate enhances for radiation parameter but decreases in variable for temperature, thermal stratification parameter, thermophoresis parameter, and Brownian parameter.

Effects of Radiation Pressure on the Elliptic Restricted Four-Body Problem

In this paper, under the effects of the largest primary radiation pressure, the elliptic restricted four-body problem is formulated in Hamiltonian form. Moreover, the canonical equations are obtained which are considered as the equations of motion. The Lagrangian points within the frame of the elliptic restricted four-body problem are obtained. The true anomalies are considered as independent variables. An analytical and numerical approach had been used. A code of Mathematica version 12 is constructed to truncate these considerations and is applied on the Earth-Moon-Sun system. In addition, the stability and periodicity of the motion about the equilibrium points are studied by using the Poincare maps. The motion about the collinear point L2 is presented as an example for the obtained results, and some families of periodic orbits are presented.

Approximations of Tangent Polynomials, Tangent –Bernoulli and Tangent – Genocchi Polynomials in terms of Hyperbolic Functions

Asymptotic approximations of Tangent polynomials, Tangent-Bernoulli, and Tangent-Genocchi polynomials are derived using saddle point method and the approximations are expressed in terms of hyperbolic functions. For each polynomial there are two approximations derived with one having enlarged region of validity.

The Eigenspace Spectral Regularization Method for Solving Discrete Ill-Posed Systems

This paper shows that discrete linear equations with Hilbert matrix operator, circulant matrix operator, conference matrix operator, banded matrix operator, TST matrix operator, and sparse matrix operator are ill-posed in the sense of Hadamard. Gauss least square method (GLSM), QR factorization method (QRFM), Cholesky decomposition method (CDM), and singular value decomposition (SVDM) failed to regularize these ill-posed problems. This paper introduces the eigenspace spectral regularization method (ESRM), which solves ill-posed discrete equations with Hilbert matrix operator, circulant matrix operator, conference matrix operator, and banded and sparse matrix operator. Unlike GLSM, QRFM, CDM, and SVDM, the ESRM regularizes such a system. In addition, the ESRM has a unique property, the norm of the eigenspace spectral matrix operator κ K = K − 1 K = 1 . Thus, the condition number of ESRM is bounded by unity, unlike the other regularization methods such as SVDM, GLSM, CDM, and QRFM.

Mathematical Analysis of the Role of HIV/HBV Latency in Hepatocytes

The biggest challenge of treating HIV is rampant liver-related morbidity and mortality. This is, to some extent, attributed to hepatocytes acting as viral reservoirs to both HIV and HBV. Viral reservoirs harbour latent provirus, rendering it inaccessible by combinational antiretroviral therapy (cART) that is specific to actively proliferating virus. Latency reversal agents (LRA) such as Shock and kill or lock and block, aiming at activating the latently infected cells, have been developed. However, they are CD4+ cell-specific only. There is evidence that the low replication level of HIV in hepatocytes is mainly due to the latency of the provirus in these cells. LRA are developed to reduce the number of latently infected cells; however, the impact of the period viral latency in hepatocytes especially, during HIV/HBV coinfection, needs to be investigated. Viral coinfection coupled with lifelong treatment of HIV/HBV necessitates investigation for the optimal control strategy. We propose a coinfection mathematical model with delay and use optimal control theory to analyse the effect of viral latency in hepatocytes on the dynamics of HIV/HBV coinfection. Analytical results indicate that HBV cannot take a competitive exclusion against HIV; thus, the coinfection endemic equilibrium implies chronic HBV in HIV-infected patients. Numerical and analytical results indicate that both HIV and HBV viral loads are higher with longer viral latency period in hepatocytes, which indicates the need to upgrade LRA to other non-CD4+ cell viral reservoirs. Higher viral load caused by viral latency coupled with the effects of cART partly explains why liver-related complications are the leading cause of mortality in HIV-infected persons.