Wound care is a common complaint in the pediatric emergency department, and depending on the type of wound, there are a myriad of options for treatment. Various options exist for analgesia and anxiolysis, including child-friendly techniques and topical, oral, intranasal, and injectable medications. Options for wound repair include nonsuture techniques, which may be favorable in children when appropriate (e.g., hair apposition technique and tissue adhesives). This chapter discusses types of wounds, analgesia, cleaning, repair of wounds (including topical adhesives, sutures, and staples), and tetanus prophylaxis. Suturing methods and various types of sutures with their respective indications are reviewed. It also discusses common complications and indications for antibiotic treatment, imaging, consultations, and disposition.