scholarly journals Minor neurological signs and behavioural function at age 2 years in neonatal hypoxic ischaemic encephalopathy (HIE)

2020 ◽  
Vol 27 ◽  
pp. 78-85 ◽  
Author(s):  
Caroline J. Edmonds ◽  
Suzannah K. Helps ◽  
Denise Hart ◽  
Anna Zatorska ◽  
Neelam Gupta ◽  
...  
Keyword(s):  
Neurological Signs ◽  
Behavioural Function

scholarly journals Epidemiology and Clinical Presentation of West Nile Virus Infection in Horses in South Africa, 2016–2017

Pathogens ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 20
Author(s):  
Freude-Marié Bertram ◽  
Peter N. Thompson ◽  
Marietjie Venter
Keyword(s):  
South Africa ◽  
West Nile Virus ◽  
Clinical Presentation ◽  
Multivariable Analysis ◽  
Late Summer ◽  
West Nile Virus Infection ◽  
Case Definition ◽  
West Nile ◽  
Prophylactic Measure ◽  
Neurological Signs

Although West Nile virus (WNV) is endemic to South Africa (RSA), it has only become recognized as a significant cause of neurological disease in humans and horses locally in the past 2 decades, as it emerged globally. This article describes the epidemiological and clinical presentation of WNV in horses across RSA during 2016–2017. In total, 54 WNV-positive cases were identified by passive surveillance in horses with febrile and/or neurological signs at the Centre for Viral Zoonoses, University of Pretoria. They were followed up and compared to 120 randomly selected WNV-negative controls with the same case definition and during the same time period. Of the WNV-positive cases, 52% had fever, 92% displayed neurological signs, and 39% experienced mortality. Cases occurred mostly in WNV-unvaccinated horses <5 years old, during late summer and autumn after heavy rain, in the temperate to warm eastern parts of RSA. WNV-positive cases that had only neurological signs without fever were more likely to die. In the multivariable analysis, the odds of WNV infection were associated with season (late summer), higher altitude, more highly purebred animals, younger age, and failure to vaccinate against WNV. Vaccination is currently the most effective prophylactic measure to reduce WNV morbidity and mortality in horses.

scholarly journals Occurrence of antibodies against Neospora caninum and/or Toxoplasma gondii in dogs with neurological signs

2011 ◽  
Vol 20 (3) ◽  
pp. 202-206 ◽  
Author(s):  
Nicolle Fridlund Plugge ◽  
Fabiano Montiani Ferreira ◽  
Rosária Regina Tesoni de Barros Richartz ◽  
Adriana de Siqueira ◽  
Rosangela Locatelli Dittrich
Keyword(s):  
Toxoplasma Gondii ◽  
Neospora Caninum ◽  
Neurological Diseases ◽  
Fluorescent Antibody ◽  
Antibody Test ◽  
Metropolitan Region ◽  
Serological Tests ◽  
Stray Dogs ◽  
Neurological Signs ◽  
Significant Difference

This study aimed to evaluate occurrences of antibodies against Neospora caninum and Toxoplasma gondii in dogs with neurological signs. Blood samples from 147 dogs were collected: 127 from owned dogs (attended at the Veterinary Teaching Hospital of the Federal University of Paraná (HV-UFPR) and at private veterinary clinics in the city of Curitiba), and 20 from stray dogs found in Curitiba's metropolitan region. The dogs presented one or more of the following neurological signs: seizures, paresis or paralysis, ataxia, behavioral abnormalities, sensory and somatic disorders and chorioretinitis. The samples were analyzed by means of the indirect fluorescent antibody test (IFAT), at a cutoff dilution of 1:50. Out of the 147 samples obtained, 17 (11.56%) were seropositive for N. caninum, 31 (21.08%) for T. gondii and four (2.72%) for both protozoa. Serum titration on the positive animals showed that 54.83% (17/31) and 41.18% (7/17) had titers > 1:200 against T. gondii and N. caninum, respectively. A significant difference in seropositivity for T. gondii (P = 0.021; OR = 2.87; CI = 1.1 > 2.8 > 7.4) was observed between owned dogs (18.11%) and stray dogs (40%). Inclusion of serological tests for neosporosis and toxoplasmosis is recommended in diagnosing neurological diseases in dogs.

Assessing behavioural function following a pyramidotomy lesion of the corticospinal tract in adult mice

2005 ◽  
Vol 195 (2) ◽  
pp. 524-539 ◽  
Author(s):  
Michelle L. Starkey ◽  
Andrew W. Barritt ◽  
Ping K. Yip ◽  
Meirion Davies ◽  
Frank P.T. Hamers ◽  
...  
Keyword(s):  
Corticospinal Tract ◽  
Adult Mice ◽  
Behavioural Function

scholarly journals Spinal dural ossification causing neurological signs in a cat

2013 ◽  
Vol 55 (1) ◽  
Author(s):  
Johanna M Antila ◽  
Janis Jeserevics ◽  
Mindaugas Rakauskas ◽  
Marjukka Anttila ◽  
Sigitas Cizinauskas
Keyword(s):  
Neurological Signs ◽  
Dural Ossification

Soft Neurological Signs

1987 ◽  
Vol 2 (3) ◽  
pp. 305-306
Author(s):  
C. R. Reynolds ◽  
G. W. Hynd
Keyword(s):  
Neurological Signs

Soft neurological signs do not increase with age in euthymic bipolar subjects

2007 ◽  
Vol 103 (1-3) ◽  
pp. 99-103 ◽  
Author(s):  
Utpal Goswami ◽  
Chinmoy Gulrajani ◽  
Anjali Varma ◽  
Aditya Sharma ◽  
Ian Nicol Ferrier ◽  
...  
Keyword(s):  
Neurological Signs

Clinical, MRI, and Histopathological Features of Hypothalamic Neuronal Hamartoma in a Young Vizsla

2021 ◽  
Author(s):  
Leonardo Bibbiani ◽  
Sara Canal ◽  
Daiana Marabese ◽  
Maria T. Mandara ◽  
Greta Foiani ◽  
...  
Keyword(s):  
Congenital Malformations ◽  
Histopathological Examination ◽  
Middle Cranial Fossa ◽  
Clinical Imaging ◽  
First Report ◽  
Histopathological Features ◽  
Neurological Signs ◽  
Cranial Fossa ◽  
The Brain ◽  
Clinical Mri

ABSTRACT Human hypothalamic neuronal hamartomas are rare, nonprogressive, congenital malformations of the hypothalamus that do not expand or metastasize to other locations. A 1 yr old female vizsla was presented for progressive intracranial multifocal neurological signs already present since adoption at 3 mo of age. MRI of the brain showed an ill-defined, intra-axial, space-occupying, nonenhancing lesion located in the ventral middle cranial fossa. Histopathological examination was consistent with hypothalamic neuronal hamartoma. This is the first report describing clinical, imaging, and histopathological features of a hypothalamic neuronal hamartoma in a dog. These findings are compared with the human counterparts.

The Effects of Methylphenidate on the Soft Neurological Signs of Hyperactive Children

PEDIATRICS ◽  
1976 ◽  
Vol 57 (4) ◽  
pp. 521-525
Author(s):  
Robert J. Lerer ◽  
M. Pamela Lerer
Keyword(s):  
Rating Scale ◽  
Teacher Rating ◽  
Neurological Status ◽  
Neurological Assessment ◽  
Subjective Test ◽  
Test Information ◽  
Neurological Signs ◽  
Teacher Rating Scale ◽  
Hyperactive Children

The neurological examination of many hyperactive children reveals the presence of abnormal neurological signs. Of 40 hyperactive children who had three or more neurological abnormalities on an initial neurological evaluation, 29 (72.5%) showed marked improvement or complete resolution of the neurological signs following treatment with methylphenidate hydrochloride (Ritalin) for 60 days. The administration of placebo did not change appreciably the neurological status of 20 hyperactive children. Improvement in behavior, which was ascertained by the use of Conners' Abbreviated Teacher Rating Scale, did not always correspond with resolution of the abnormal neurological signs. This finding suggests that methylphenidate affects behavioral and motoric functions separately and independently. Repeat neurological assessment, looking for resolution of abnormal neurological signs, should be included as part of the follow-up medical examination in treated hyperactive children. Coupled with other objective and subjective test information, improvement of the neurological status provides supportive evidence of overall improvement in the hyperactive child who is receiving drug therapy.

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