Impact of magnetite iron oxide nanoparticles on wheat ( Triticum aestivum L.) development: Evaluation of oxidative damage

2016 ◽  
Vol 131 ◽  
pp. 77-88 ◽  
Author(s):  
María Florencia Iannone ◽  
María Daniela Groppa ◽  
María Elisa de Sousa ◽  
Marcela Beatriz Fernández van Raap ◽  
María Patricia Benavides
Keyword(s):  
Triticum Aestivum ◽  
Iron Oxide ◽  
Oxidative Damage ◽  
Iron Oxide Nanoparticles ◽  
Triticum Aestivum L ◽  
Oxide Nanoparticles ◽  
Development Evaluation

Seed Priming with Iron Oxide Nanoparticles Triggers Iron Acquisition and Biofortification in Wheat (Triticum aestivum L.) Grains

2018 ◽  
Vol 38 (1) ◽  
pp. 122-131 ◽  
Author(s):  
Naveen Sundaria ◽  
Manoj Singh ◽  
Prateek Upreti ◽  
Ravendra P. Chauhan ◽  
J. P. Jaiswal ◽  
...  
Keyword(s):  
Triticum Aestivum ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Iron Acquisition ◽  
Seed Priming ◽  
Triticum Aestivum L ◽  
Oxide Nanoparticles

Assessment of oxidative damage induced by iron oxide nanoparticles on different nervous system cells

2019 ◽  
Vol 845 ◽  
pp. 402989 ◽  
Author(s):  
Natalia Fernández-Bertólez ◽  
Carla Costa ◽  
Maria João Bessa ◽  
Margriet Park ◽  
Marie Carriere ◽  
...  
Keyword(s):  
Nervous System ◽  
Iron Oxide ◽  
Oxidative Damage ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles

Responses of wheat (Triticum aestivum) plants grown in a Cd contaminated soil to the application of iron oxide nanoparticles

2019 ◽  
Vol 173 ◽  
pp. 156-164 ◽  
Author(s):  
Afzal Hussain ◽  
Shafaqat Ali ◽  
Muhammad Rizwan ◽  
Muhammad Zia ur Rehman ◽  
Muhammad Farooq Qayyum ◽  
...  
Keyword(s):  
Triticum Aestivum ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Contaminated Soil ◽  
Oxide Nanoparticles

scholarly journals Effect of raw and purified carbon nanotubes and iron oxide nanoparticles on the growth of wheatgrass prepared from the cotyledons of common wheat (triticum aestivum)

2018 ◽  
Vol 5 (1) ◽  
pp. 103-114 ◽  
Author(s):  
Seung Mook Lee ◽  
Pavan M. V. Raja ◽  
Gibran L. Esquenazi ◽  
Andrew R. Barron
Keyword(s):  
Carbon Nanotubes ◽  
Triticum Aestivum ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Common Wheat ◽  
Human Population ◽  
Oxide Nanoparticles

The increase in global production of nanomaterials has raised concern as to their possible effects on plants that could ultimately affect the human population.

scholarly journals Cytotoxicity and genotoxicity of iron oxide nanoparticles: An in vitro biosafety study

2016 ◽  
Vol 68 (1) ◽  
pp. 41-50 ◽  
Author(s):  
Erdal Sonmez ◽  
Elanur Aydin ◽  
Hasan Turkez ◽  
Elvan Özbek ◽  
Basak Togar ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Oxidative Damage ◽  
Cell Viability ◽  
Iron Oxide Nanoparticles ◽  
Human Blood ◽  
Blood Cells ◽  
Biological Effects ◽  
Oxide Nanoparticles ◽  
Human Blood Cells ◽  
Dose Dependent

With the development of nanotechnology and the wide use of iron oxide nanoparticles, it has become necessary to assess the potential adverse biological effects of magnetite. This study investigated the cytotoxicity, genotoxicity and oxidative damage of different concentrations of magnetite (0 to 1000 mg/L) in human whole blood cultures. After supplementation of magnetite, the blood samples were incubated for 72 h. Cell viability was assessed by the 3-(4,5-dimethyl-thiazol-2-yl) 2,5-diphenyltetrazolium bromide (MTT) and lactate dehydrogenase (LDH) release assays. The total antioxidant capacity (TAC) and total oxidant status (TOS) were determined to evaluate the dose-dependent effects of magnetite on the oxidant/antioxidant balance and to evaluate the potential oxidative injury due to increased oxidative stress. Genotoxicity was estimated by by the sister chromatid exchange (SCE), micronuclei (MN) and chromosome aberration (CA) assays and determination of 8-oxo-2-deoxyguanosine (8-OH-dG) levels. The results of MTT and LDH assays showed that the higher concentrations of magnetite (100, 150, 300, 500 and 1000 mg/L) decreased cell viability. Concentrations of magnetite higher than 10 mg/L increased TOS levels and decreased TAC levels in human blood cells. Increasing concentrations of magnetite caused significant increases in MN, SCE and CA rates and 8-OH-dG levels. The obtained results showed that magnetite exerted dose-dependent effects on oxidative damage, genotoxicity and cytotoxicity in human blood cells.

TARGETING CYCLIN B1 WITH ANTISENSE OLIGONUCLETOTIDES- COATED SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES

2018 ◽  
Vol 6 (10) ◽  
Author(s):  
Hosam Zaghloul ◽  
Doaa A. Shahin ◽  
Ibrahim El- Dosoky ◽  
Mahmoud E. El-awady ◽  
Fardous F. El-Senduny ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Cellular Uptake ◽  
Superparamagnetic Iron Oxide ◽  
Cyclin B1 ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Mcf7 Cells ◽  
M Phase ◽  
The Impact

Antisense oligonucleotides (ASO) represent an attractive trend as specific targeting molecules but sustain poor cellular uptake meanwhile superparamagnetic iron oxide nanoparticles (SPIONs) offer stability of ASO and improved cellular uptake. In the present work we aimed to functionalize SPIONs with ASO targeting the mRNA of Cyclin B1 which represents a potential cancer target and to explore its anticancer activity. For that purpose, four different SPIONs-ASO conjugates, S-M (1–4), were designated depending on the sequence of ASO and constructed by crosslinking carboxylated SPIONs to amino labeled ASO. The impact of S-M (1–4) on the level of Cyclin B1, cell cycle, ROS and viability of the cells were assessed by flowcytometry. The results showed that S-M3 and S-M4 reduced the level of Cyclin B1 by 35 and 36%, respectively. As a consequence to downregulation of Cyclin B1, MCF7 cells were shown to be arrested at G2/M phase (60.7%). S-M (1–4) led to the induction of ROS formation in comparison to the untreated control cells. Furthermore, S-M (1–4) resulted in an increase in dead cells compared to the untreated cells and SPIONs-treated cells. In conclusion, targeting Cyclin B1 with ASO-coated SPIONs may represent a specific biocompatible anticancer strategy.

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