scholarly journals Fabrication and characterization of freeze dried strontium-doped bioactive glasses/chitosan composite scaffolds for biomedical engineering

Author(s):  
Chao-Kuang Kuo ◽  
Hsiang-Wei Huang ◽  
Liu-Gu Chen ◽  
Yu-Jen Chou
2006 ◽  
Vol 514-516 ◽  
pp. 1005-1009 ◽  
Author(s):  
José V. Araújo ◽  
J.A. Lopes da Silva ◽  
Margarida M. Almeida ◽  
Maria Elisabete V. Costa

Porous chitosan/brushite composite scaffolds were prepared by a freeze-drying technique, starting from brushite suspensions in chitosan solutions. The obtained scaffolds showed a regular macroporous and interconnected structure with brushite particles uniformly distributed in the chitosan matrix. The variation of the brushite concentration affected the microstructure of the final freeze-dried scaffold, in particular, its porosity and its average pore size. The yield strengths of the composite scaffolds could also be improved by the increase of the brushite content.


2015 ◽  
Vol 54 ◽  
pp. 20-25 ◽  
Author(s):  
Hye-Lee Kim ◽  
Gil-Yong Jung ◽  
Jun-Ho Yoon ◽  
Jung-Suk Han ◽  
Yoon-Jeong Park ◽  
...  

2005 ◽  
Vol 75A (2) ◽  
pp. 275-282 ◽  
Author(s):  
Lijun Kong ◽  
Yuan Gao ◽  
Wenling Cao ◽  
Yandao Gong ◽  
Nanming Zhao ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Fujian Zhao ◽  
Xiongfa Ji ◽  
Yang Yan ◽  
Zhen Yang ◽  
Xiaofeng Chen ◽  
...  

The repair of bone defects in load-bearing positions still faces great challenges. Tantalum (Ta) has attempted to repair bone defects based on the excellent mechanical properties. However, the osseointegration of Ta needs to be improved due to the lack of osteoinduction. Herein, tantalum–gelatin–methacryloyl–bioactive glass (Ta–GelMA–BG) scaffolds were successfully fabricated by loading BG in 3D-printed Ta scaffolds through a chemical crosslinking method. The results showed that the composite scaffolds have the ability to promote cell adhesion and proliferation. The incorporation of BG resulted in a significant increase in apatite-forming and osteogenesis differentiation abilities. In vivo results indicated that the Ta–GelMA–BG scaffolds significantly enhanced the osteointegration at the early stage after implantation. Overall, the Ta–GelMA–BG scaffolds are a promising platform for the load bearing bone regeneration field.


2012 ◽  
Vol 66 (1) ◽  
pp. 36-38 ◽  
Author(s):  
Hairong Liu ◽  
Leilei Xia ◽  
Yao Dai ◽  
Man Zhao ◽  
Zheng Zhou ◽  
...  

2016 ◽  
Vol 56 (9) ◽  
pp. 983-991 ◽  
Author(s):  
Anuj Kumar ◽  
Kummara Madhusudana Rao ◽  
Adnan Haider ◽  
Sung Soo Han ◽  
Tae Won Son ◽  
...  

2018 ◽  
Vol 7 (2) ◽  
pp. 99-102
Author(s):  
Dalveer Singh ◽  
Sandeep Singh ◽  
Gurpreet Singh

Glasses are common in use now days. These are used in different applications like domestic, automobile, telecommunication etc. The glasses are very useful materials because of their impressive properties. Few years back a new generation of glasses were developed i.e. bioactive glasses and bioactive glass ceramics. The glasses are used for bone grafting now-a-days because of their impressive bioactive properties. These glasses have tendency to form bonds with the living tissue organs. The future of these glasses will be bright in dental, orthopedics and prosthetic applications. In the present work borosilicate glasses of different compositions have been studied. The different elements were added with appropriate mol% to compose a new bioglass composition. The samples were prepared by melt quench route. The samples were immersed for 21 days in SBF. The samples were characterized before and after immersion in SBF by different techniques. The XRD technique was done to confirm the amorphous nature of glass before immersion and after immersion. The SEM and EDX were done to check the changes on the surface after immersion. The sample S1 has better biocompatibility results than S2 andS3. The formation of apatite on the glass samples were confirmed by all techniques mentioned above.


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