Within the framework of Space@Sea project, an articulated modular floating structurewas developed to serve as building blocks for artificial islands. The modularity was one of the keyelements, intended to provide the desired flexibility of additional deck space at sea. Consequently, the layout of a modular floating concept may change, depending on its functionality and environmental condition. Employing a potential-flow-based numerical model (i.e., weakly nonlinear Green function solver AQWA), this paper studied the hydrodynamic sensitivity of such multibody structures to the number of modules, to the arrangement of these modules, and to the incident wave angle. Results showed that for most wave frequencies, their hydrodynamic characteristics were similar although the floating platforms consisted of a different number of modules. Only translational horizontal motions, i.e., surge and sway, were sensitive to the incident wave angle. The most critical phenomenon occurred at head seas, where waves traveled perpendicularly to the rotation axes of hinged joints, and the hinge forces were largest. Hydrodynamic characteristics of modules attached behind the forth module hardly changed. The highest mooring line tensions arose at low wave frequencies, and they were caused by second-order mean drift forces. First-order forces acting on the mooring lines were relatively small. Apart from the motion responses and mooring tensions, forces acting on the hinge joints governed the system’s design. The associated results contribute to design of optimal configurations of moored and articulated multibody floating islands.