Development of a Mapping Program to Teach Online-Based Financial Accounting Courses During the COVID-19 Pandemic

The purpose of this research was to develop a mapping program for online-based teaching, using the instructional learning design based on ICT. Developing the mapping program consisted of three stages: the analysis stage, design stage and development stage, where each step had an output that supported the process of content development of the learning media. This mapping program is expected to support online learning for the Financial Accounting course during the COVID-19 Pandemic. Keywords: Financial Accounting, Mapping Program, Online-Based Financial Accounting Courses

Injection with Toxoplasma gondii protein affects neuron health and survival

Toxoplasma gondii is an intracellular parasite that causes a long-term latent infection of neurons. Using a custom MATLAB-based mapping program in combination with a mouse model that allows us to permanently mark neurons injected with parasite proteins, we found that Toxoplasma-injected neurons (TINs) are heterogeneously distributed in the brain, primarily localizing to the cortex followed by the striatum. In addition, we determined that cortical TINs are commonly (>50%) excitatory neurons (FoxP2+) and that striatal TINs are often (>65%) medium spiny neurons (MSNs) (FoxP2+). By performing single neuron patch-clamping on striatal TINs and neighboring uninfected MSNs, we discovered that TINs have highly aberrant electrophysiology. As approximately 90% of TINs will die by 8 weeks post-infection, this abnormal physiology suggests that injection with Toxoplasma protein— either directly or indirectly— affects neuronal health and survival. Collectively, these data offer the first insights into which neurons interact with Toxoplasma and how these interactions alter neuron physiology in vivo.

Analysis of Sedimentation for The Optimization of Lempake Dam Operations for Flood Control for The City of Samarinda, Province of East Kalimantan

The Lempake Dam currently functions as a dam that provides raw water for irrigation and clean water, besides its indirect functioning as the only flood control dam in the Karangmumus sub-watershed. Current conditions indicate that the Lempake Reservoir has experienced decreased capacity from year to year. At the normal water level, the reservoir capacity of Lempake Reservoir in 2013 was 0.76 million m3 and in 2018 was 0.39 million m3. Therefore, efforts are needed to control reservoir sedimentation and reservoir operations to allow the Lempake Dam to continue to function as a flood control reservoir. This study was carried out by analyzing the volume of sedimentation in the reservoir using the ArcGIS program and analyzing the flood hydrograph at the site by flood routing at the Pasar Segiri River, optimizing reservoir operations, and mapping flood inundation using the RAS Mapping program (HEC-RAS). The results showed that the storage volume in 2020 is predicted to be 0.241 million m3 with an annual sediment rate of 0.074 million m3. From the flood routing analysis and optimization of reservoir operations, the cross-sectional capacity of the river in Pasar Segiri (safe limit elevation +3.30 m) is insufficient for a flood discharge of a return period of more than 2 years (more than 222.14 m3/sec) for Scenario 1, and of more than 5 years (more than 320.48 m3/sec) for Scenario 2

The Private Impact of Public Data: Landsat Satellite Maps Increased Gold Discoveries and Encouraged Entry

How does public data shape the relative performance of incumbents and entrants in the private sector? Using a simple theoretical framework, I argue that public data reduces investment uncertainty, facilitates the discovery of new market opportunities, and increases the relative market share of new entrants relative to incumbents. I shed light on these predictions by estimating the impact of public data from Landsat, a U.S. National Aeronautics and Space Administration satellite mapping program, on the discovery rates of new deposits by incumbents (seniors) and entrants (juniors) in the gold exploration industry. I exploit idiosyncratic timing variation and cloud cover in Landsat coverage across regions to identify the causal effect of public data on the patterns of gold discovery. I find that Landsat data nearly doubled the rate of significant gold discoveries after a region was mapped and increased the market share of new entrants from about 10% to 25%. Public data seem to play an important, yet relatively underexplored, role in driving performance differences across firms. This paper was accepted by Ashish Arora, entrepreneurship and innovation.

Sediments and bedform mapping of the Lower Saxony Wadden Sea and North Sea (Germany)

<p>Seafloor mapping is the subject of several worldwide research programs dealing with the growing awareness that changes of the marine environmental conditions have to be accurately monitored. The monitoring requirements strongly stimulate the scientific interest in innovative mapping methods and tools, which should be exploitable within the extensive mapping programs carried out by governmental agencies and institutes.</p><p>The Coastal Research Station within the NLWKN is carrying out a long-term program to map subtidal areas of the Lower Saxony coastal and marine waters, adopting a methodological approach aimed to increase objectivity and repeatability of results.</p><p>The study area is one of the world’s largest tidal system encompassing a multitude of transitional zones between land, marine, and estuarine environments. The geological and geomorphological setting is closely related to the Late Quaternary evolution of the North Sea and the actual morphodynamic processes. The seabed is made of Holocene sand to silt deposits and peat layers. They overlay Pleistocene fluvioglacial deposits, made of sands, rocks, and boulders, which locally outcrop in small areas of the North Sea and in the deepest sectors of the Wadden Sea tidal inlets.</p><p>Even though existing maps provide a good broad-scaled representation of the sediments distribution, they were produced by the interpolation of grab-samples therefore lacking of spatial resolution and bedforms characterization. The ongoing mapping program provides full-coverage detailed sedimentological and geomorphological data, by means of swath-bathymetrical systems, subbottom profiler, and validation samples. The methodological approach integrates bathymetric, backscatter, and stratigraphic information to characterize bedforms and substrates. Bathymetry and seabed images are interpreted using geomorphometric as well as object-based image analysis, to increase the objectivity and generate reproducible results.</p><p>Maps outline common sedimentological and geomorphological features across all the observed Wadden Sea tidal inlets, which are made of fine sandy sediments and narrow outcrops of peat layers on the main tidal channels slopes. Both erosive and depositional geomorphological processes are present, represented by several orders of scarps, mainly connected to alternations of hard-substrates and unconsolidated sands, and medium to very large sand waves. Moreover, data reveal high-resolution information about hard-substrate outcrops in the North Sea area.</p><p>The mapping program provides new detailed geological-geomorphological features of a very dynamic coastal area, using repeatable and objective methods. The combination of different datasets and tools allows the quantitative analysis of the complex subtidal morphology, the correlation of bedforms and substrates. Resulting products will be further developed for habitat mapping purposes and morphological and hydro-dynamical modelling.</p>

Toxoplasma gondii injected neurons localize to the cortex and striatum and have altered firing

Toxoplasma gondii is an intracellular parasite that causes a long-term latent infection of neurons. Using a custom MATLAB-based mapping program in combination with a mouse model that allows us to permanently mark neurons injected with parasite proteins, we found that Toxoplasma-injected neurons (TINs) are heterogeneously distributed in the brain, primarily localizing to the cortex followed by the striatum. Using immunofluorescence co-localization assays, we determined that cortical TINs are commonly (>50%) excitatory neurons (FoxP2+) and that striatal TINs are often (>65%) medium spiny neurons (MSNs) (FoxP2+). As MSNs have highly characterized electrophysiology, we used ex vivo slices from infected mice to perform single neuron patch-clamping on striatal TINs and neighboring uninfected MSNs (bystander MSNs). These studies demonstrated that TINs have highly abnormal electrophysiology, while the electrophysiology of bystander MSNs was akin to that of MSNs from uninfected mice. Collectively, these data offer new neuroanatomic and electrophysiologic insights into CNS toxoplasmosis.