Background: 3D object detection based on point clouds in road scenes has attracted much attention recently. The voxel-based methods voxelize the scene to regular grids, which can be processed with the advanced feature learning frameworks based on convolutional layers for semantic feature learning. The point-based methods can extract the geometric feature of the point due to the coordinate reservations. The combination of the two is effective for 3D object detection. However, the current methods use a voxel-based detection head with anchors for classification and localization. Although the preset anchors cover the entire scene, it is not suitable for detection tasks with larger scenes and multiple categories of objects, due to the limitation of the voxel size. Additionally, the misalignment between the predicted confidence and proposals in the Regions of the Interest (ROI) selection bring obstacles to 3D object detection. Methods: We investigate the combination of voxel-based methods and point-based methods for 3D object detection. Additionally, a voxel-to-point module that captures semantic and geometric features is proposed in the paper. The voxel-to-point module is conducive to the detection of small-size objects and avoids the presets of anchors in the inference stage. Moreover, a confidence adjustment module with the center-boundary-aware confidence attention is proposed to solve the misalignment between the predicted confidence and proposals in the regions of the interest selection. Results: The proposed method has achieved state-of-the-art results for 3D object detection in the Karlsruhe Institute of Technology and Toyota Technological Institute (KITTI) object detection dataset. Actually, as of September 19, 2021, our method ranked 1st in the 3D and Bird Eyes View (BEV) detection of cyclists tagged with difficulty level ‘easy’, and ranked 2nd in the 3D detection of cyclists tagged with ‘moderate’. Conclusions: We propose an end-to-end two-stage 3D object detector with voxel-to-point module and confidence adjustment module.